Stiffing Cancer

Stiffing Cancer Stiffing Cancer Stiffing CancerWhen considering krebs detection, people often think of obvious signs such as external symptoms or blood counts. But the stiffness of cells inside the body can actually be a vital clue. Cancer cells, for example, tend to be softer than healthy ones. If researchers can observe this softness, instead of physically probing for it, then cancer detection may be possible without using laser-oriented optical tweezers or other methods that damage the cells.But how do you isolate this stiffness variable in order to measure it? MIT engineers, armed with an old Albert Einstein equation, have come up with a noninvasive method to gauge a cells stiffness by using standard confocal microscopy and film to observe the motion of its particles. Measuring a cells stiffness this way could be a key to not just finding cancer but monitoring its progress throughout treatment.Prof. Ming Guo at his lab. Image MITMing Guo, assistant professor of mechanical enginee ring at MIT, and his team faced the challenge partly by using the Stokes-Einstein equation, created by Albert Einstein.During my PhD, I was looking at the dynamics of a cell when a system is under cell equilibrium, Guo explains. There are a lot of classic diffusion laws that have principles explained by Einstein.However, what about cells not under thermal equilibrium? Long-term research followed, which led to tweaking the equation to measure movement caused by physical force, not temperature. Guos lab had been mainly doing experiments using optical tweezers, which can use the force of a laser, for example, to manipulate microscopic objects. That force, however, can damage cells.So we developed in the lab direct imaging to look at the movements of particles, he says. This helps with the understanding of the non-equilibrium nature, and we can translate this movement.Guo likens this to the final touches on your morning coffee. The stirring of the spoon for the sugar is causing movement but so is the temperature. In this case, the researchers want to figure out the equivalent of the spoons role in the movement.To do so, the researchers used a modified version of Stokes-Einstein to find the cells stiffness and, by filming the cell and watching each frame, they could separate the influence of temperature on the movement and focus on the physical forces. That eliminates the need to use optical tweezers and prevents the cells from being harmed.The method needs further testing before its introduced to real-life medical scenarios, but Guo is optimistic.Doctors want to be confident enough in this that it can truly be a supplement, he says, adding that the team also wants to use the method to monitor the ongoing health of cancer patients. We hope this can help fight cancer better.Eric Butterman is an independent writer. For Further Discussion Doctors want to be confident enough in this that it can truly be a supplement. Prof. Ming Guo, MIT

Customize this Outstanding Attorney Resume 1

Customize this Outstanding Attorney Resume 1Customize this Outstanding Attorney Resume 1Create Resume LITIGATION Successfully conducted litigation in a variety of high-profile cases.Achieved favorable resolution of complex, often difficult to win cases.Practiced before administrative boards and arbitrators.Attained numerous credits in all phases of civil litigation in state and federal courts.EXPERIENCE Barnham And Haynes, Washington, D.C. Senior Associate, January 1996 PresentRepresented a diverse group of clients in civil litigation matters. Met with clients and developed trial strategy based on clients needs and recommendations. Litigated each case in full. Consistently achieved favorable results for clients, including two verdicts in which the settlement exceeded $2 million.Bayne And Associates, Baltimore, MDAssociate Attorney, August 1990 January 1996 Member of trial team that successfully defended Norton Co. in its $6 million coverage litigation. Prepared and argued motions. Defended depositions. Drafted settlement conference brief.EDUCATION Jun. 88J.D., Yale Law School, New Haven, CTActivities Editor of Law ReviewCoach, Yale Debate SocietyJun. 84B.A., History And Government, University of Michigan, Ann Arbor, MIHonors Summa Cum LaudeBeikney Award for most outstanding thesis in history.National Finalst, Expemporaneous Speaking, AFAPROFESSIONAL AFFILIATIONS Member of the Bar, State of Virginia, admitted 1990Contributor, The Western Law Review Consultant, Equity And Legal Assistance FoundationMember, Board of Directors, YMCAs of Greater D.C.Member, Virginia NARL BoardCustomize Resume

How to Pitch Your Value Dissecting the Elevator Pitch

How to Pitch Your Value Dissecting the Elevator PitchHow to Pitch Your Value Dissecting the Elevator PitchDevelop a strong elevator pitch that highlights your key skill sets, passions, and job goals.Q How do you implement the correct pitch with the right words that describe me and my skills? Gregory R. A When you think about it, an elevator pitch is just one of the many methods youll use to communicate your personal brand to a potential employer.As a job seeker, you instantly become a sales and marketing professional. You are now in the business of marketing your skills and expertise to people connected to your target job. Your messaging needs to be consistent across all of your branding channels, your resume, deckblatt letter, and online profiles what you say when networking and how you respond to questions in an interview.By taking the time to go through this exercise and craft your pitch, you will be better prepared to communicate your value through every leiter of the job searc h.TimingYou typically have 15 to 45 seconds to explain your intrinsic value to a potential employer. This is your amuse bouche to the conversation your introduction and tagline. The idea is to whet the persons appetite so they want to continue talking with you. Think about the TV commercials you watch on average, they last between 15 to 60 seconds because researchers have found that anything longer causes viewers to switch channels or tune out. Similarly, you want your pitch to be short (and interesting) enough to hold the persons attention.ContentThe elevator pitch is all about showing employers what you bring to the table what you can do for them. In short, you want to explain (1) who you are (2) what you are great at and passionate about, and (3) how your strengths will value a potential employer. Dont try to stuff in too many details stick to the three fruchtwein important traits. Try this brainstorming exercise to help you create this pitch.Who are you?Write down your name, job title and primary function.What are you great at and passionate about?Think back to your job goals. Why are you targeting this type of work in the first distributionspolitik? What do you like about it or find interesting? Dont start with the fassonal, politically correct response you assume the recruiter is looking for. Be honest with yourself. Each time you write down a response, ask yourself why? again to see if you can dig any deeper.How has your previous experience helped prepare you for this role? Consider the different projects and assignments youve completed during your career what results have you produced? If possible, review previous performance evaluations or other forms of feedback youve received. What key skills or areas of expertise make you good at what you like to do?How do your key strengths bring value to a potential employer? Now that youve written down what youre great at doing, its time to elaborate on the results youve produced. What accomplishments are y ou proud of? What were the tangible results? Did you increase revenue, cut costs, or make things run mora efficiently? Try to think in terms of better, faster or cheaper. At the end of the day, what have you done for past employers?Review everything youve written down. You may even want to read it aloud to a friend or family member to help brainstorm. What information sticks out to you? Whats memorable and shows your passion? Now, identify your hook. Whats the nugget you want people to remember you for? This will become your tagline. For instance, when people ask me what I do, I usually use some form of the followingMy name is Amanda Augustine and I am a Job Search Expert and Career Coach. For mora than ten years, Ive worked with Ladders to educate and prepare millions of professionals for the job-search process through the development of coaching programs, live recruiting events and online advice in my weekly column, Ask Amanda . Ive dedicated almost 3 years to testing various tech niques to identify the best ways to navigate the job search landscape in todays marketplace. My passion is helping people find the right job, sooner.In addition to this pitch, I recommend creating a short list of 3-5 stories you can use to demonstrate and quantify your work further. These stories should be simple talking points (think of the STAR approach ) that youve thought through ahead of time.DeliveryPractice makes perfect. I dont care how great the content is if you recite your pitch in a monotone voice, youre not going to impress anyone. Ask a friend or fellow job seeker to help you practice your pitch. I know it can be uncomfortable, but you need to practice saying your pitch out loud. The more you practice, the more natural it will feel. You can also try recording your pitch and playing it back to hear what you sound like. Consider the following points when critiquing your pitchDid you stay within the 15-45 second timeframe?Were you talking too quickly, slowly, softly or l oudly?Was it conversational enough, or did it sound too rehearsed?Were a lot of filler words (um like) or a particular phrase used repeatedly?How was your energy level?Did you sound confident?Was it genuine?Was it memorable?Once youve got the basics down, consider how you would alter your pitch to suit different occasions. Think about how you would respond to the tell me about yourself question when youre having a drink with some friends, versus what you would say during an industry trade show or networking event.Deliver your personal branding statement with passion and sincerity, and youll be golden.How to Pitch Your Value Dissecting the Elevator PitchDevelop a strong elevator pitch that highlights your key skill sets, passions, and job goals.Q How do you implement the correct pitch with the right words that describe me and my skills? Gregory R. A When you think about it, an elevator pitch is just one of the many methods youll use to communicate your personal brand to a potential employer.As a job seeker, you instantly become a sales and marketing professional. You are now in the business of marketing your skills and expertise to people connected to your target job. Your messaging needs to be consistent across all of your branding channels, your resume, cover letter, and online profiles what you say when networking and how you respond to questions in an interview.By taking the time to go through this exercise and craft your pitch, you will be better prepared to communicate your value through every phase of the job search.TimingYou typically have 15 to 45 seconds to explain your intrinsic value to a potential employer. This is your amuse bouche to the conversation your introduction and tagline. The idea is to whet the persons appetite so they want to continue talking with you. Think about the TV commercials you watch on average, they last between 15 to 60 seconds because researchers have found that anything longer causes viewers to switch channels or tune out. Similarly, you want your pitch to be short (and interesting) enough to hold the persons attention.ContentThe elevator pitch is all about showing employers what you bring to the table what you can do for them. In short, you want to explain (1) who you are (2) what you are great at and passionate about, and (3) how your strengths will value a potential employer. Dont try to stuff in too many details stick to the three most important traits. Try this brainstorming exercise to help you create this pitch.Who are you?Write down your name, job title and primary function.What are you great at and passionate about?Think back to your job goals. Why are you targeting this type of work in the first place? What do you like about it or find interesting? Dont start with the formal, politically correct response you assume the recruiter is looking for. Be honest with yourself. Each time you write down a response, ask yourself why? again to see if you can dig any deeper.How has your previous e xperience helped prepare you for this role? Consider the different projects and assignments youve completed during your career what results have you produced? If possible, review previous performance evaluations or other forms of feedback youve received. What key skills or areas of expertise make you good at what you like to do?How do your key strengths bring value to a potential employer? Now that youve written down what youre great at doing, its time to elaborate on the results youve produced. What accomplishments are you proud of? What were the tangible results? Did you increase revenue, cut costs, or make things run more efficiently? Try to think in terms of better, faster or cheaper. At the end of the day, what have you done for past employers?Review everything youve written down. You may even want to read it aloud to a friend or family member to help brainstorm. What information sticks out to you? Whats memorable and shows your passion? Now, identify your hook. Whats the nugg et you want people to remember you for? This will become your tagline. For instance, when people ask me what I do, I usually use some form of the followingMy name is Amanda Augustine and I am a Job Search Expert and Career Coach. For more than ten years, Ive worked with Ladders to educate and prepare millions of professionals for the job-search process through the development of coaching programs, live recruiting events and online advice in my weekly column, Ask Amanda . Ive dedicated almost 3 years to testing various techniques to identify the best ways to navigate the job search landscape in todays marketplace. My passion is helping people find the right job, sooner.In addition to this pitch, I recommend creating a short list of 3-5 stories you can use to demonstrate and quantify your work further. These stories should be simple talking points (think of the STAR approach ) that youve thought through ahead of time.DeliveryPractice makes perfect. I dont care how great the content is if you recite your pitch in a monotone voice, youre not going to impress anyone. Ask a friend or fellow job seeker to help you practice your pitch. I know it can be uncomfortable, but you need to practice saying your pitch out loud. The more you practice, the more natural it will feel. You can also try recording your pitch and playing it back to hear what you sound like. Consider the following points when critiquing your pitchDid you stay within the 15-45 second timeframe?Were you talking too quickly, slowly, softly or loudly?Was it conversational enough, or did it sound too rehearsed?Were a lot of filler words (um like) or a particular phrase used repeatedly?How was your energy level?Did you sound confident?Was it genuine?Was it memorable?Once youve got the basics down, consider how you would alter your pitch to suit different occasions. Think about how you would respond to the tell me about yourself question when youre having a drink with some friends, versus what you would say during an industry trade show or networking event.Deliver your personal branding statement with passion and sincerity, and youll be golden.